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Xeljanz Linked to Blood Clots in Lungs

Xeljanz and Xeljanz XR (tofacitinib) are very costly bio-engineered drugs made by Pfizer that have been prescribed to treat rheumatoid arthritis, psoriatic arthritis and moderate-to-severe ulcerative colitis.

When taken for rheumatoid arthritis and ulcerative colitis, Pfizer recommended that it be taken twice a day in 10mg doses.

The drugs, which can cost a patient up to $50,000 a year, generated $1.77 billion in sales for Pfizer in 2018.

A just released post-marketing trial study found that at that dosage the drug caused a very high incidence of pulmonary embolisms – blood clots that got caught in one of the arteries that go from the heart to the lungs, blocking the normal flow of blood.

Such blockages (pulmonary embolisms) often caused serious to fatal problems, including damage to patients’ lungs and harm to multiple organs due to lower oxygen levels in patients’ blood. In some instances patients died because a single clot became so large that it cut off the blood flow, or an artery became clogged by multiple small clots.

The FDA issued a Safety Alert on February, 25, 2019, for Xeljanz and Xeljanz XR (tofacitinib) for increased risk of blood clots in the lungs and death with the higher dosage of the drug (10mg/2 times per day) used by Rheumatoid Arthritis patients.

Speak to your doctor before considering any changes to your medications. Seek medical attention immediately if you are experiencing any of the following while taking tofacitinib:

  • Clammy or blue-colored skin
  • Coughing up blood
  • Chest or back pain
  • Excessive sweating

If you or a loved one developed pulmonary embolism (or one or more blood clots in your lungs) after taking two 10mg doses of Xeljanz or Xeljanz XR per day, you may be entitled to compensation. Call us toll free or fill out our case review form. Our legal team is here to help and quick to respond to all inquiries.

The information and articles contained on or linked from Advocate Law Group P.C.’s website are provided for general informational purposes only, and are not intended as legal advice on any subject matter, nor as a solicitation or invitation to establish a client relationship with Advocate. Although Advocate may assist clients who reside in many jurisdictions, it only does so from offices in states where its lawyers are authorized to practice and in association with qualified admitted counsel in all other jurisdictions. We recommend that people always seek the legal advice of competent counsel in their jurisdiction and never base a decision to retain a lawyer solely on a website or any form of advertisement. Unless otherwise stated, the photos used on this website are stock photos rather than photos of Advocate’s attorneys, staff or clients.
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