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Xeljanz Linked to Blood Clots in Lungs
Xeljanz and Xeljanz XR (tofacitinib) are very costly bio-engineered drugs made by Pfizer that have been prescribed to treat rheumatoid arthritis, psoriatic arthritis and moderate-to-severe ulcerative colitis.
When taken for rheumatoid arthritis and ulcerative colitis, Pfizer recommended that it be taken twice a day in 10mg doses.
The drugs, which can cost a patient up to $50,000 a year, generated $1.77 billion in sales for Pfizer in 2018.
A just released post-marketing trial study found that at that dosage the drug caused a very high incidence of pulmonary embolisms – blood clots that got caught in one of the arteries that go from the heart to the lungs, blocking the normal flow of blood.
Such blockages (pulmonary embolisms) often caused serious to fatal problems, including damage to patients’ lungs and harm to multiple organs due to lower oxygen levels in patients’ blood. In some instances patients died because a single clot became so large that it cut off the blood flow, or an artery became clogged by multiple small clots.
The FDA issued a Safety Alert on February, 25, 2019, for Xeljanz and Xeljanz XR (tofacitinib) for increased risk of blood clots in the lungs and death with the higher dosage of the drug (10mg/2 times per day) used by Rheumatoid Arthritis patients.
Speak to your doctor before considering any changes to your medications. Seek medical attention immediately if you are experiencing any of the following while taking tofacitinib:
- Clammy or blue-colored skin
- Coughing up blood
- Chest or back pain
- Excessive sweating
If you or a loved one developed pulmonary embolism (or one or more blood clots in your lungs) after taking two 10mg doses of Xeljanz or Xeljanz XR per day, you may be entitled to compensation. Call us toll free or fill out our case review form. Our legal team is here to help and quick to respond to all inquiries.